Clinical trials are a type of clinical research that involves testing whether a new intervention is safe and effective in people. The goal of these interventions is to treat or prevent a health condition and improve or stabilize patient outcomes.
Examples of interventions include a drug, device, exercise, diet, or approach to care. Clinical trials may compare an intervention to a placebo or compare two or more interventions to each other by randomly assigning participants to groups.
Within the Department of Physical Medicine and Rehabilitation, our portfolio of clinical trials includes industry-sponsored and investigator-initiated studies that span conditions such as Stroke, Duchenne Muscular Dystrophy, Spinal Muscular Atrophy, Amyotrophic Lateral Sclerosis, Charcot Marie Tooth Disease, Myasthenia Gravis, and Aging. Please see the table below for more details, including an overview of ongoing studies, contact information, and links to study details and investigator profiles.
| Study Name | Sponsor / Funding Agency | (Site) Principal Investigator | MU Contact |
|---|
| Safety and Efficacy of NMD670 in Ambulatory Adult Patients with Type 3 Spinal Muscular Atrophy | NMD Pharma A/S | W. David Arnold, MD | Neetha Gali, Clinical Trials Coordinator, ngdcd@missouri.edu |
| A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity. (DIRECTION) | Ipsen | Joseph E. Burris, MD | Anne Bonnett, Nurse Clinician, bonnetta@missouri.edu |
| Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury (PATTERN) | Merz | Joseph E. Burris, MD | Anne Bonnett, Nurse Clinician, bonnetta@missouri.edu |
| A Study of CAP-1002 in Ambulatory and Non-ambulatory Patients with Duchenne Muscular Dystrophy (HOPE-3) | Capricor Inc. | Jane Anne Emerson, MD | Mehgan Willis, Clinical Research Nurse, willismj@missouri.edu |
| HEALEY ALS Platform Trial | Multiple | Vovanti Jones, MD | Anne Bonnett, Nurse Clinician, bonnetta@missouri.edu |
| Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults with Myasthenia Gravis | Kansas City Consortium for Musculoskeletal Diseases | Kristina M. Kelly, PT, DPT, MS, EdM, NCS, CPT, PES | Kristina Kelly, Assistant Research Professor, kristina.kelly@health.missouri.edu |
