If an MU investigator would like to use de-identified tissue and data, the MU OneHealth Biorepository (OHB) can act as an honest broker. Investigators should follow these steps:

  1. Log in to eCompliance
  2. Click on IRB forms
  3. Click on Human subjects research determination
  4. Fill out. Feel free to list OHB as your honest broker.
  5. Submit

Please feel free to contact the OHB with questions.

Prior to distribution, the OHB must have received documentation from IRB confirming that they have reviewed and no IRB is required.


Acting as an honest broker, the OHB can de-identify specimens. The 18 elements that cannot be shared with the investigator and must be removed by the OHB can be found below.

HIPAA Privacy Rule in Research

  1. Names
  2. All geographic subdivisions smaller than a state, including street address, city, county, precinct, ZIP code, and their equivalent geographical codes, except for the initial three digits of a ZIP code if according to the current publicly available data from the Bureau of the Census:
    • The geographic unit formed by combining all ZIP Codes with the same three initial digits contains more than 20,000 people.
    • The initial three digits of a Zip Code for all such geographic units containing 20,000 or fewer people are changed to 000.
  3. Dates:
    • Birth date
    • Admission date
    • Discharge date
    • Date of death
    • All ages over 89 and all elements of dates (including year) indicative of such age except that a single category of 90 or older
  4. Telephone numbers
  5. Fax numbers
  6. Electronic mail addresses
  7. Social security numbers
  8. Medical record numbers
  9. Health plan beneficiary numbers
  10. Account numbers
  11. Certificate/license numbers
  12. Vehicle identifiers and serial numbers, including license plate numbers
  13. Device identifiers and serial numbers
  14. Web Universal Resource Locators (URLs)
  15. Internet Protocol (IP) address numbers
  16. Biometric identifiers, including finger and voice prints
  17. Full face photographic images and any comparable images
  18. Any other unique identifying number, characteristic, or code
    • The covered entity does not have actual knowledge that the information could be used alone or in combination with other information to identify an individual who is a subject of the information.